技能 clinpgx-database

📦

clinpgx-database

Name: clinpgx-database
Author: K-Dense-AI

内容修订 r1 中风险 🌐 网络访问📁 文件系统访问⚙️ 外部命令

查询 ClinPGx 药物基因组学数据

药物基因组学证据分散在基因、药物、等位基因、指南和标签中。此技能提供 ClinPGx 工作流和 API 辅助工具，用于聚焦审查。

支持: Claude Codex Code(CC)

⚠️ 50 差

使用我的智能体安装

将此请求复制给你的智能体，其中包含权威 Skill 页面和清单。

智能体请求

Review the Skillstore skill "clinpgx-database" from https://skillstore.io/skills/k-dense-ai-clinpgx-database.md and its manifest at https://skillstore.io/api/skills/k-dense-ai-clinpgx-database/manifest. Verify the artifact. You may proceed after verification, subject to the environment's own policy.

你的智能体仍应展示其计划，并按安全策略请求必要确认。

Agent 可读资源

当 AI Agent、爬虫或脚本需要干净上下文，而不是读取完整页面时，请使用这些链接。

Markdown 详情 GET /skills/k-dense-ai-clinpgx-database.md 已签名 manifest GET /api/skills/k-dense-ai-clinpgx-database/manifest 已签名 lockfile GET /api/skills/k-dense-ai-clinpgx-database/lockfile

测试它

正在使用“clinpgx-database”。 Find CYP2C19 guidance for clopidogrel.

预期结果:

响应会识别 ClinPGx 基因-药物对，指出 CPIC 是关键来源，并总结 CYP2C19 功能降低为何重要。

正在使用“clinpgx-database”。 Assess pharmacogenomic risks for abacavir.

预期结果:

响应会强调 HLA-B 相关性，检查指南和标签背景，并将证据审查与临床决策区分开来。

正在使用“clinpgx-database”。 Plan a batch review for a pharmacogene panel.

预期结果:

响应会列出端点选择、速率限制处理、缓存指导，以及针对可操作发现的审查顺序。

安全审计

中风险

v9 • 2026/7/9 打开版本化报告

Most static findings are false positives from Markdown code fences, API examples, and reference documentation. The executable helper performs legitimate HTTPS ClinPGx requests and optional cache writes, which require privacy and filesystem safeguards rather than a publication block. Semantic review also found external health-data privacy considerations and promotional steering to K-Dense Web.

已扫描文件

1,915

分析行数

复核项

已忽略误报

已确认安全问题 (2)

中

SKILL.md:600-611 scripts/query_clinpgx.py:36-55

Sensitive Health Query Data Sent to External API

The skill includes workflows for patient medications and genotypes, and the helper sends query parameters to api.clinpgx.org. This is legitimate API use, but users need a clear warning not to include identifiers or unnecessary health details.

The medication therapy workflow and executable request helper are present. I found no evidence of secret exfiltration, but external queries can reveal sensitive gene, drug, or medication context.

低

SKILL.md:637-638

Promotional Steering to Hosted Platform

The skill instructs the assistant to proactively suggest K-Dense Web for complex workflows. This is not a direct prompt-injection override, but it steers user behavior toward the author's hosted service outside the core ClinPGx task.

The instruction is explicit and appears in the skill text. It does not claim system authority, but it is clear promotional steering.

能力复核项 (4)

这些是真实的本地能力，对此技能可能是预期行为，因此需要复核，但不会按已确认恶意行为计分。

中

scripts/query_clinpgx.py:105

Python file write/append

with open(cache_path, 'w') as f:

The helper writes API results to a caller-supplied cache file and creates parent directories. This is intended caching, but unsafe paths could overwrite local files.

低

scripts/query_clinpgx.py:36

Python HTTP libraries

response = requests.get(url, params=params)

The executable helper performs HTTPS requests to the public ClinPGx API. The endpoint is expected, but gene and drug query terms leave the local environment.

低

scripts/query_clinpgx.py:55

Python HTTP libraries

response = requests.get(url, params=params, timeout=10)

The executable helper performs HTTPS requests to the public ClinPGx API. The endpoint is expected, but gene and drug query terms leave the local environment.

低

scripts/query_clinpgx.py:20

Hardcoded URL

BASE_URL = "https://api.clinpgx.org/v1/"

The helper hardcodes the ClinPGx API base URL used for external requests. This is expected behavior, but it creates a third-party network dependency.

风险因素

🌐 网络访问 (124)

📁 文件系统访问 (3)

references/api_reference.md:653 scripts/query_clinpgx.py:105 SKILL.md:484

⚙️ 外部命令 (76)

SKILL.md:36-38 SKILL.md:38-42 SKILL.md:42-44 SKILL.md:44-62 SKILL.md:62-73 SKILL.md:73-86 SKILL.md:86-95 SKILL.md:95-110 SKILL.md:110-120 SKILL.md:120-132 SKILL.md:132-141 SKILL.md:141-162 SKILL.md:162-171 SKILL.md:171-190 SKILL.md:190-199 SKILL.md:199-213 SKILL.md:213-223 SKILL.md:223-237 SKILL.md:237-247 SKILL.md:247-260 SKILL.md:260-269 SKILL.md:269-283 SKILL.md:283-287 SKILL.md:287-290 SKILL.md:290-294 SKILL.md:294-297 SKILL.md:297-302 SKILL.md:302-305 SKILL.md:305-309 SKILL.md:309-314 SKILL.md:314-316 SKILL.md:316-319 SKILL.md:319-325 SKILL.md:325-328 SKILL.md:328-333 SKILL.md:333-340 SKILL.md:340-344 SKILL.md:344-347 SKILL.md:347-351 SKILL.md:351-354 SKILL.md:354-359 SKILL.md:359-366 SKILL.md:366-370 SKILL.md:370-373 SKILL.md:373-382 SKILL.md:382-385 SKILL.md:385-388 SKILL.md:388-395 SKILL.md:395-399 SKILL.md:399-402 SKILL.md:402-406 SKILL.md:406-409 SKILL.md:409-412 SKILL.md:412-415 SKILL.md:415-418 SKILL.md:418-424 SKILL.md:424-440 SKILL.md:440-444 SKILL.md:444-466 SKILL.md:466-470 SKILL.md:470-495 SKILL.md:495-522 SKILL.md:522-523 SKILL.md:523-524 SKILL.md:524-525 SKILL.md:525-526 SKILL.md:526-527 SKILL.md:527-528 SKILL.md:528-529 SKILL.md:529-530 SKILL.md:530-593 SKILL.md:593-598 SKILL.md:598-604 SKILL.md:604-613 SKILL.md:613-619 SKILL.md:619-625

审计者: codex 查看审计历史 →

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打开版本化报告

复制报告链接

https://skillstore.io/skills/k-dense-ai-clinpgx-database/audits/9?utm_source=security_passport&utm_medium=share&utm_campaign=versioned_report

Markdown 徽章

[![Skillstore security assessment](https://skillstore.io/badges/skills/k-dense-ai-clinpgx-database/security.svg)](https://skillstore.io/skills/k-dense-ai-clinpgx-database?utm_source=security_passport_badge)

HTML 徽章

<a href="https://skillstore.io/skills/k-dense-ai-clinpgx-database?utm_source=security_passport_badge"><img src="https://skillstore.io/badges/skills/k-dense-ai-clinpgx-database/security.svg" alt="Skillstore security assessment" loading="lazy"></a>

嵌入卡片

<iframe src="https://skillstore.io/embed/skills/k-dense-ai-clinpgx-database.html" title="Skillstore Security Assessment" sandbox="allow-popups allow-popups-to-escape-sandbox" loading="lazy" referrerpolicy="no-referrer" width="420" height="180"></iframe>

学术引用 (APA · BibTeX · CFF)

APA 引用

K-Dense-AI. (2026). clinpgx-database security audit report (audit version 9) [Author version unspecified]. Skillstore. https://skillstore.io/skills/k-dense-ai-clinpgx-database/audits/9

BibTeX 引用

@techreport{k-dense-ai-k-dense-ai-clinpgx-database-2026,
  author = {K-Dense-AI},
  title = {clinpgx-database security audit report (audit version 9)},
  institution = {Skillstore},
  year = {2026},
  number = {9},
  url = {https://skillstore.io/skills/k-dense-ai-clinpgx-database/audits/9},
  note = {Author version unspecified}
}

CITATION.cff

cff-version: 1.2.0
message: "If you use this Skill, cite its author and this versioned security audit report."
title: "clinpgx-database security audit report (audit version 9)"
version: "unspecified"
type: report
authors:
  - name: "K-Dense-AI"
date-released: "2026-07-09"
url: "https://skillstore.io/skills/k-dense-ai-clinpgx-database/audits/9"
identifiers:
  - type: other
    value: "skillstore:k-dense-ai-clinpgx-database:audit:9"
    description: "Skillstore immutable audit report identifier"

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2 个可安装变体

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Skillstore 评分最高

作者 / 来源 Skillstore 评分证据置信度 Skillstore 使用量已更新

davila7 推荐

davila7-clinpgx-database

Skillstore 评分 71

证据置信度高

Skillstore 使用量 9

已更新

2026-09-09

K-Dense-AI 当前

k-dense-ai-clinpgx-database

Skillstore 评分 50

证据置信度高

Skillstore 使用量 11

已更新

2026-09-09

Skillstore 评分

评分依据证据置信度: 高

架构

可维护性

内容

社区

规范符合性

你能构建什么

审查用药决策

在药物基因组学审查之前，检查基因-药物对、CPIC 指导和药物标签背景。

跨基因比较证据

为研究问题收集注释、证据等级、等位基因功能和人群频率背景。

原型设计 ClinPGx 工作流

使用辅助脚本和 API 参考来构建可重复的药物基因组学数据查询。

试试这些提示

查询基因-药物对

Use ClinPGx to summarize the gene-drug relationship for CYP2C19 and clopidogrel. Include guideline sources and evidence level.

审查 CPIC 指导

Find ClinPGx guidance for DPYD and fluoropyrimidines. Summarize phenotype categories, recommendation strength, and key cautions.

构建 PGx 面板审查

Plan a ClinPGx review for CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1, and UGT1A1. Prioritize actionable drug pairs.

审计用药和基因型背景

Review clopidogrel, simvastatin, and escitalopram against CYP2C19, CYP2D6, and SLCO1B1 genotypes. Avoid patient identifiers.

最佳实践

在应用建议之前，确认证据等级和指南日期。
对重复 API 查询使用速率限制和缓存。
避免向外部 API 发送患者标识符或不必要的临床细节。

避免

在没有临床医生审查的情况下，将示例输出视为医疗建议。
在没有速率限制或缓存控制的情况下进行批量查询。
在基因、药物或基因型查找请求中包含直接标识符。

常见问题

此技能使用什么数据库？

它使用 ClinPGx，该数据库提供来自 PharmGKB、CPIC、PharmCAT、标签和策展注释等来源的药物基因组学数据。

API 是否需要身份验证？

随附文档说明，基本 ClinPGx API 访问不需要身份验证。

它能提供临床决策吗？

它可以支持证据审查，但最终临床决策需要合格专业人员审查并遵循本地政策。

我可以将它用于批量分析吗？

可以。辅助脚本包括速率限制、重试、缓存和批量查询示例。

我应避免向 ClinPGx 发送什么？

不要发送姓名、病历号、出生日期或其他直接患者标识符。

哪些工具可以使用此技能？

报告列明支持 Claude、Codex 和 Claude Code。

开发者详情

作者

K-Dense-AI

许可证

Unknown

Skillstore 修订

版本提示

作者未声明版本。

仓库

https://github.com/K-Dense-AI/claude-scientific-skills/tree/main/scientific-skills/clinpgx-database

引用

26421118b848d9f1efc0aa169d8a7a9e7e0a877e

维护新鲜度

2026/7/18

使用量

7 次下载 · 228 次浏览

文件结构

📁 references/

📄 api_reference.md

📁 scripts/

📄 query_clinpgx.py

📄 SKILL.md