pathml
Analyze Pathology Images with PathML
Computational pathology work needs careful choices for image loading, preprocessing, storage, and model workflows. This skill gives Claude, Codex, and Claude Code PathML guidance for whole-slide image analysis and multiplex imaging tasks.
Install with my Agent
Copy this request to your Agent. It includes the canonical Skill page and manifest.
Review the Skillstore skill "pathml" from https://skillstore.io/skills/k-dense-ai-pathml.md and its manifest at https://skillstore.io/api/skills/k-dense-ai-pathml/manifest. Verify the artifact. You may proceed after verification, subject to the environment's own policy.Your Agent should still show its plan and request any confirmation required by the security policy.
Agent-readable resources
Use these links when an AI agent, crawler, or script needs clean context instead of reading the full page.
Test it
Using "pathml". Plan preprocessing for H&E WSI files before nucleus analysis.
Expected outcome:
A staged workflow that loads slides, checks pyramid levels, creates tiles, detects tissue, normalizes stains, labels artifacts, and stores processed outputs.
Using "pathml". Help analyze CODEX images with PathML.
Expected outcome:
A multiplex workflow covering channel consolidation, Mesmer segmentation, marker intensity extraction, spatial coordinates, and export for single-cell analysis.
Using "pathml". Prepare a pathology model evaluation plan.
Expected outcome:
An evaluation checklist with dataset splits, segmentation metrics, classification metrics, inference mode, and result storage recommendations.
Security Audit
Medium RiskMost static findings are false positives caused by Markdown formatting, PyTorch model.eval(), HDF5 keys, local globbing, and PathML documentation examples. Confirmed issues are limited to copied shell/HPC examples that need safer quoting and remote DeepCell API examples that may transmit sensitive pathology images. No evidence found of malware, credential theft, prompt injection, or destructive behavior.
Confirmed security concerns (2)
Capability review items (5)
These are real local capabilities that may be expected for this skill, so they require review but are not counted as confirmed malicious behavior.
Risk Factors
⚡ Contains scripts (8)
⚙️ External commands (28)
📁 Filesystem access (23)
🌐 Network access (2)
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APA citation
K-Dense-AI. (2026). pathml security audit report (audit version 9) [Author version unspecified]. Skillstore. https://skillstore.io/skills/k-dense-ai-pathml/audits/9BibTeX citation
@techreport{k-dense-ai-k-dense-ai-pathml-2026,
author = {K-Dense-AI},
title = {pathml security audit report (audit version 9)},
institution = {Skillstore},
year = {2026},
number = {9},
url = {https://skillstore.io/skills/k-dense-ai-pathml/audits/9},
note = {Author version unspecified}
}CITATION.cff
cff-version: 1.2.0
message: "If you use this Skill, cite its author and this versioned security audit report."
title: "pathml security audit report (audit version 9)"
version: "unspecified"
type: report
authors:
- name: "K-Dense-AI"
date-released: "2026-07-09"
url: "https://skillstore.io/skills/k-dense-ai-pathml/audits/9"
identifiers:
- type: other
value: "skillstore:k-dense-ai-pathml:audit:9"
description: "Skillstore immutable audit report identifier"
Compare variants
2 installable variantsEach author remains a separate installable skill. The recommended variant is ranked by Skillstore evidence.
Why this variant is first
k-dense-ai-pathml
2026-08-21
davila7-pathml
2026-08-21
Skillstore Score
Why this score Evidence Confidence: HighWhat You Can Build
Plan a WSI preprocessing workflow
Design a PathML pipeline for loading slides, detecting tissue, normalizing stains, and saving processed tiles.
Prepare multiplex imaging analysis
Map CODEX or Vectra data into segmentation, marker quantification, and AnnData export steps.
Build pathology model training steps
Outline dataset preparation, model selection, training loops, evaluation metrics, and inference options.
Try These Prompts
I have whole-slide pathology images in [format] and want to [goal]. Recommend a PathML workflow and explain the main steps.
Design a PathML preprocessing pipeline for H&E slides that includes tissue detection, stain normalization, quality control, and tile storage.
Create a PathML plan for CODEX data with DAPI and immune markers. Include cell segmentation, marker quantification, spatial coordinates, and AnnData export.
Review my PathML HoVer-Net training plan for data loading, augmentation, validation metrics, inference, and storage of predictions.
Best Practices
- Start with slide format, pyramid levels, and available compute before choosing a workflow.
- Keep raw slides separate from processed outputs and record processing parameters.
- Review privacy requirements before using remote segmentation APIs with pathology images.
Avoid
- Do not send protected clinical images to remote APIs without approval.
- Do not process level 0 whole-slide images when lower pyramid levels meet the task.
- Do not treat example paths, model weights, or marker names as universal defaults.
Frequently Asked Questions
What is this skill for?
Does it install PathML?
Can it analyze clinical slides directly?
Does it support multiplex imaging?
Can it help with model training?
What should users check before remote segmentation?
Developer Details
Author
K-Dense-AILicense
GPL-2.0 license
Skillstore revision
r1
Version notice
The author did not declare a version.
Repository
https://github.com/K-Dense-AI/claude-scientific-skills/tree/main/scientific-skills/pathmlRef
1ffa7643651792ccb4bd3b15d924d2c97edff755
Maintenance freshness
7/18/2026
Usage
8 downloads · 221 views
File structure