adaptyv
Submit protein sequences for cloud lab validation
Also available from: davila7
Protein design requires experimental validation. Adaptyv provides API access to a cloud laboratory for automated testing of binding affinity, expression levels, thermostability, and enzyme activity. Get experimental results in approximately 21 days.
Download the skill ZIP
Upload in Claude
Go to Settings → Capabilities → Skills → Upload skill
Toggle on and start using
Test it
Using "adaptyv". Submit two antibody sequences for binding assays against PD-L1
Expected outcome:
- Experiment submitted successfully
- Experiment ID: exp_new123xyz
- Status: submitted
- Estimated completion: 2025-02-07
- Target: Human PD-L1
Using "adaptyv". What is the status of my binding experiment?
Expected outcome:
- Experiment: exp_abc123xyz
- Status: processing
- Progress: 65%
- Current stage: assay
- Updated: 2025-01-25T14:30:00Z
Using "adaptyv". Download and summarize the binding results
Expected outcome:
- Results downloaded: exp_abc123xyz_results.json
- Sequences tested: 12
- Top binder: variant_7 (KD: 0.8 nM)
- Confidence: high (R-squared: 0.98)
Security Audit
Low RiskAll 304 static findings are FALSE POSITIVES. The skill is legitimate scientific software for protein research. Scanner patterns triggered on: FASTA format headers (protein sequences in markdown code blocks), API calls to official platform endpoints, environment variable usage for API keys (recommended practice), and scientific notation (e.g., binding affinity values like 1.2e-9). No malicious behavior confirmed.
Risk Factors
⚡ Contains scripts (3)
🌐 Network access (2)
🔑 Env variables (2)
Quality Score
What You Can Build
Antibody affinity testing
Submit antibody variants to measure binding affinity against target antigens and identify high-affinity candidates.
Sequence optimization validation
Use computational tools to design protein variants, then experimentally validate expression and stability predictions.
Catalytic activity screening
Screen enzyme variants for improved turnover, substrate affinity, and inhibitor sensitivity.
Try These Prompts
Submit my antibody sequences to Adaptyv for binding assays against human PD-L1. The sequences are in FASTA format and I want to measure KD values.
Check the status of experiment exp_abc123xyz and tell me the current stage and estimated completion date.
Download the results from experiment exp_abc123xyz and parse the binding measurements into a table showing sequence, KD, kon, and koff values.
Optimize my protein sequences using NetSolP and SolubleMPNN, then submit the top 50 candidates to Adaptyv for expression testing with webhook notification.
Best Practices
- Pre-screen sequences with computational tools (NetSolP, ESM) before experimental submission to reduce costs
- Use webhooks instead of polling for experiment completion notifications
- Include wild-type or reference sequences as controls in every batch submission
Avoid
- Submitting sequences without validation - always run computational screening first
- Polling for status instead of using webhooks - wastes API quota and adds delay
- Ignoring FASTA format requirements - validate sequences locally before submission
Frequently Asked Questions
How long does it take to get results?
How do I get API access?
What experiment types are supported?
Can I test binding against custom targets?
How many sequences can I submit?
How are results delivered?
Developer Details
Author
K-Dense-AILicense
MIT
Repository
https://github.com/K-Dense-AI/claude-scientific-skills/tree/main/scientific-skills/adaptyvRef
main
File structure