Skills adaptyv
🧬

adaptyv

Low Risk ⚡ Contains scripts🌐 Network access🔑 Env variables

Submit protein sequences for cloud lab validation

Also available from: davila7

Protein design requires experimental validation. Adaptyv provides API access to a cloud laboratory for automated testing of binding affinity, expression levels, thermostability, and enzyme activity. Get experimental results in approximately 21 days.

Supports: Claude Codex Code(CC)
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Test it

Using "adaptyv". Submit two antibody sequences for binding assays against PD-L1

Expected outcome:

  • Experiment submitted successfully
  • Experiment ID: exp_new123xyz
  • Status: submitted
  • Estimated completion: 2025-02-07
  • Target: Human PD-L1

Using "adaptyv". What is the status of my binding experiment?

Expected outcome:

  • Experiment: exp_abc123xyz
  • Status: processing
  • Progress: 65%
  • Current stage: assay
  • Updated: 2025-01-25T14:30:00Z

Using "adaptyv". Download and summarize the binding results

Expected outcome:

  • Results downloaded: exp_abc123xyz_results.json
  • Sequences tested: 12
  • Top binder: variant_7 (KD: 0.8 nM)
  • Confidence: high (R-squared: 0.98)

Security Audit

Low Risk
v4 • 1/17/2026

All 304 static findings are FALSE POSITIVES. The skill is legitimate scientific software for protein research. Scanner patterns triggered on: FASTA format headers (protein sequences in markdown code blocks), API calls to official platform endpoints, environment variable usage for API keys (recommended practice), and scientific notation (e.g., binding affinity values like 1.2e-9). No malicious behavior confirmed.

6
Files scanned
3,608
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findings
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Total audits
Audited by: claude View Audit History →

Quality Score

38
Architecture
100
Maintainability
87
Content
29
Community
90
Security
91
Spec Compliance

What You Can Build

Antibody affinity testing

Submit antibody variants to measure binding affinity against target antigens and identify high-affinity candidates.

Sequence optimization validation

Use computational tools to design protein variants, then experimentally validate expression and stability predictions.

Catalytic activity screening

Screen enzyme variants for improved turnover, substrate affinity, and inhibitor sensitivity.

Try These Prompts

Submit binding assay
Submit my antibody sequences to Adaptyv for binding assays against human PD-L1. The sequences are in FASTA format and I want to measure KD values.
Check experiment status
Check the status of experiment exp_abc123xyz and tell me the current stage and estimated completion date.
Download results
Download the results from experiment exp_abc123xyz and parse the binding measurements into a table showing sequence, KD, kon, and koff values.
Run optimization pipeline
Optimize my protein sequences using NetSolP and SolubleMPNN, then submit the top 50 candidates to Adaptyv for expression testing with webhook notification.

Best Practices

  • Pre-screen sequences with computational tools (NetSolP, ESM) before experimental submission to reduce costs
  • Use webhooks instead of polling for experiment completion notifications
  • Include wild-type or reference sequences as controls in every batch submission

Avoid

  • Submitting sequences without validation - always run computational screening first
  • Polling for status instead of using webhooks - wastes API quota and adds delay
  • Ignoring FASTA format requirements - validate sequences locally before submission

Frequently Asked Questions

How long does it take to get results?
Most experiments deliver results in approximately 21 days from submission.
How do I get API access?
Contact support@adaptyvbio.com to request access during the alpha/beta period.
What experiment types are supported?
Binding assays (BLI), expression testing, thermostability (DSF), and enzyme activity assays.
Can I test binding against custom targets?
Yes, use the POST /targets/request endpoint to request custom antigens not in the catalog.
How many sequences can I submit?
Up to 1000 experiments per day per organization with batch submissions recommended.
How are results delivered?
Results are available via API download with raw data URLs and quality metrics including confidence scores.